Prof. Soo Khee Chee started his surgical practice in Farrer Park Hospital and Farrer Park Medical Centre with an interest in surgical oncology and head and neck surgery.

After his medical and surgical training, Prof. Soo returned to Singapore General Hospital in 1988 and has been there since. In 1993, Prof. Soo became Head of the Department of Surgery in Singapore General Hospital and held that position for 11 years. For a period, he was the Chair of the NUS Department of Surgery.

In 1995, he was awarded an MD from NUS for his academic research thesis. Prof. Soo has mentored a number of general surgeons, head and neck surgeons and surgical oncologists. In 1997, Prof. Soo became the Founding Director of the National Cancer Centre Singapore and served in that position for 20 years. He was also the Senior Vice Dean of Duke NUS Medical School and now continues to hold the Benjamin Sheares Professorship in Academic Medicine.

Prof. Soo Khee Chee studied medicine in the National University of Singapore graduating in 1975. He did his surgical training in Sydney and then had his fellowship training in surgical oncology and head and neck surgery in London and New York.